Functional network antagonism and consciousness

Abstract Spontaneous brain activity changes across states of consciousness. A particular consciousness-mediated configuration is the anticorrelations between default mode network and other regions. What this antagonistic organization implies about consciousness to date remains inconclusive. In Perspective Article, we propose that are physiological expression concept segregation, namely brain’s capacity show selectivity in way areas will be functionally connected. We postulate effect mediated by process neural inhibition, regulating global local inhibitory activity. While recognizing can also result from mechanisms, inhibition helps understanding how metastability affected after disrupting balance. combination with relevant theories consciousness, suggest a prior work as marker preserved predict if not state host anticorrelations, then most likely individual does entertain subjective experience. believe link underlying physiology help only comprehend happens, but conceptualize effective interventions for treating disorders which seem particularly affected.